Tim Springer (Founder): His Scientific and Otherwise Life

Timothy A. Springer received his B.A. in Biochemistry from University of California in 1971, his Ph.D. in Molecular Biology and Biochemistry from Harvard in 1976 and did a fellowship with Cesar Milstein in Cambridge, England. Dr. Springer is Latham Family Professor of Biological Chemistry and Molecular Pharmacology and Professor of Medicine at Harvard Medical School and Boston Children’s Hospital.

Harvard Medical School and Boston Children's Hospital
Professor of Medicine at Harvard Medical School and Boston Children's Hospital
Timothy Springer, Founder, portrait photo
leukocyte emigration diagram

Dr. Springer discovered many of the adhesion molecules of the immune and circulatory systems and the  paradigm for leukocyte emigration from the bloodsteam by which white blood cells patrol the body to detect infection and accumulate to fight disease.

This work led to founding LeukoSite in 1993, which developed three drugs approved by the FDA.

Press Release announcing Millenium Pharmaceuticals purchase of Leukocyte

This work led to numerous honors: Crafoord Prize, the American Association of Immunologists Meritorious Career Award, the Stratton Medal from the American Society of Hematology, and the Basic Research Prize from the American Heart Association. Springer is a member of the National Academy of Sciences.

Timothy Springer, featured in the Harvard University Gazette

Tim worked as a VISTA volunteer 1967-1968. He helped the Yomba Shoshone Tribe draft Tribal Resolutions, helped the tribe lobby Nevada for a paved road that now allows their children to live at home while they attend high school, started a 4-H club, and led teenagers in the Neighborhood Youth Corps Program. This picture is from his return to the Yomba Shoshone Reservation to re-unite with his teenage group. He lived in the house in the background. The only running water was in a nearby spring, and there was no electricity or heat aside from a wood stove.

Timothy Springer

Springer’s academic interests now focus on how protein conformational change together with tensile force activates integrins, von Willebrand factor, and the transforming growth factor-B family.

Magazines covers where Timothy Springer has been published

He has invested in Selecta since the B round and is currently a Board member. He is a founding investor in Moderna and Editas Medicine. He is a founder, investor, and board member of Scholar Rock and Morphic Therapeutic.

Diagram, highlighting term Scientist, along with Board Member, investor, founder
silhouette of person gazing up into a romantic sky

He is currently working on multiple non-profits, including an institute to advance entrepreneurship and innovation in protein therapeutics and a malaria vaccine.

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